Review6-7 - FullReviewSheet(67 Monday,June02,2008 10:48PM...

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Full Review Sheet (6-7) Monday, June 02, 2008 10:48 PM Lecture 6   Developmental   Genetics   Drosophila  common fruit fly, 13,000 genes, 180Mbp genome, 12 day life cycle Drosophila Development  - single nucleus in cytoplasm, 70 minutes of nuclear division creates  syncytium, 90 minutes - nuclei migrates to periphery of cytoplasm, 2 hours - syncytial  blastoderm - pole cycles migrate to the edge to form germ cells, 3 hours - cellular blastoderm  forms,  C Elegan - microscopic worm - 19,000 genes, 97Mbp genome, 3.5 day life cycle,  Homeosis  - mutants lack a structure which is replaced by structure normally found elsewhere Ultrabithorax  - drosophila mutation - mutant has a second set of wings instead of halteres Antennapedia (Antp)  – legs in place of antennae Hox Genes - transcription factors of homeodomain family, found in 2 gene complexes - found in  the same order in which they act on the organism during development, 
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  • Spring '08
  • Genetics, Developmental Genetics, segment polarity genes, maternal effect genes, organization Zygotic Genes, genotype Maternal­effect genes, gradient Gap Genes

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Review6-7 - FullReviewSheet(67 Monday,June02,2008 10:48PM...

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