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Unformatted text preview: body, is synthesized during pregnancy by the placenta. The general structure of estriol is shown below. HO OH OH estriol Identify any stereocentres (chiral centres) present in estriol, and state how many stereoisomeric forms of the molecule exist. 2. Ibuprofen, the anti-inflammatory agent used in Advil and Motrin, is a chiral molecule. Only the ( S )-isomer is effective; the ( R )-isomer has no anti-inflammatory action. O HO Ibuprofen Identify the stereocentre in ibuprofen and draw its ( S )-isomer using 3D perspective at the stereocentre. 2 3. Shown below are Newman projections for ( R,R )-, ( S,S )- and ( R,S )-2,3-butanediol. a) Which is which? b) Which, if any, of the above Newman projections represent meso compounds? c) What is the stereochemical relationship between the different stereoisomers? CH 3 H OH CH 3 HO H CH 3 H OH CH 3 H OH CH 3 HO H CH 3 HO H...
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This note was uploaded on 12/22/2010 for the course CHM CHM138 taught by Professor Andrewdicks during the Spring '09 term at University of Toronto.
- Spring '09