2010 2010 histology study guide 2010 - Study Guide This...

Study Guide
This guide is to be used in conjunction with, and as an adjunct to, the online syllabus (sections are
printed by you as you require them, or you can purchase a B&W version from the bookstore), the online
images, laboratory sessions and the TBL (team-based learning MANDATORY laboratory sessions).
COURSE DIRECTOR: Roger J. Bick, FAHA, MMedEd, CBiol, MIBiol MBS.
COURSE CO-ORDINATOR: Linda Dalton, Health Education Officer
LAB LEADERS:Roger J. Bick, Diane L.M. Bick PhD, Keri Smith, PhD, Angel Paredes, PhD, Barry
Rittman, PhD
LECTURERS: Diane Bick, Roger Bick, Marylee Kott, Barry Rittman, Michael Covinsky, Keri Smith,
Judianne Kellaway, Erin Furr Stimming, Margaret Uthman,
Rhonda Ghorbani.
CHAIRMAN: Robert L. Hunter Jr., MD, PhD
GOALS, AIMS AND OBJECTIVES
MS1 Histology introduces the medical student to a large vocabulary of basic science terms. This course
contains the basis of cell biology, tissue microstructure and function, and the microanatomy of the organ
systems, taught in a functional way. That is, we don’t ask “what cell is this?” we are more likely to ask
“what cell is this and what does it produce/do/synthesize/control?”
This course is offered early in the year to provide you with knowledge that helps bridge the gap between
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a number of the basic sciences, as well as serving to introduce structures and concepts that are studied
in depth in physiology, pharmacology and pathology. Wherever possible, the clinical significance and
application to subsequent courses is stressed via the TBL (MANDATORY) laboratory sessions and the
clinical correlates that follow the post-lab sessions. Employing these clinical ‘excursions’ has been shown
to help students in Clinical Applications (part of ICM), improve student-student interactions, improve
grades (Really!) and give you a head start for Problem Based Learning in your second year.
When you have finished this course you will be able to describe how cells and extracellular components
of the human body are composed and arranged to form tissues and organs. You will be able to
recognize the microscopic structure of many of the cells and tissues using the light microscope and in
electron micrographs. An ability to relate this knowledge and understanding to gene function and protein
synthesis, as well as to cellular functions, interactions and the roles of extracellular structures, should be
achieved. You will astound people in the future with your depth of knowledge.
STUDY OBJECTIVES
I. INTRODUCTION (METHODS)
1. List the methods used to visualize the arrangement and composition of cells and tissues
and state some of the general principles of tissue fixation, staining, localization and
examination, which permit accurate interpretation.
2. Describe the meaning of commonly used terms in histologic methods, such as
histochemistry, cytochemistry, immunochemistry, in situ hybridization, radioautography,
etc.