CONNECTIVE TISSUE (I) PROPER
Roger J. Bick
Gartner & Hiatt, Chapter 3; Klein and McKenzie, p77-93
List components of ground substance.
List major fiber types found in connective tissue matrix.
List 5 types of collagen and their respective distributions.
Identify the cell types of connective tissue proper, their origins, and major functions.
Recognize and classify 3 types of adult connective tissue proper.
Review the composition of the basement membrane.
Mesenchyme, fibroblast, macrophage, Kupffer cell, plasma cell, eosinophil, mast
cell, collagen, ground substance, basement membrane
COMPOSITION OF CONNECTIVE TISSUE
embedded in an
extracellular matrix (ECM)
Composed of ground substance, fibers, and tissue fluid.
The variation in the cells and components of the ECM is responsible for
the different types of connective tissue throughout the body.
Functions in a wide variety of supportive and protective roles.
A colorless, transparent mixture of proteins found between the cells and fibers of
High viscosity contributes to its role as a lubricant and a physical barrier
to penetration by bacteria.
Composed of glycosaminoglycans (GAGs), proteoglycans, and
Long, non-branched polysaccharide chains consisting of repeating
All are sulfated, except hyaluronic acid, and have a
strong negative charge.
Hyaluronic acid, chondroitin sulfate, dermatan sulfate, heparan sulfate,
and keratan sulfate.