IB 132 - Summer 2009 - Mau - Midterm 1

IB 132 - Summer 2009 - Mau - Midterm 1 - IB132Summer2009

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IB132 Summer 2009 Name: ___________________________________ Human Physiology Midterm 1 Instructions: Please mark your name on this page and any pages with short answer/free response. Please put your name and ID number on your scantron. You may write all over this exam to help you narrow down your choices, but then select the best answer to each question and mark it on your scantron in pencil. Short answer and fill-in questions at the end should be written in the given space in pen. You have until 4PM. Good luck! Potentially useful equations: E=mc 2 J = P A(C o -C i ) E ion = (61/z) log([C o ]/[C i ]) V m =61 log P k [K o ]+P Na [Na o ]+P Cl [Cl i ] F= P/R R = 8 L CO= SV x HR MAP=CO x TPR P k [K i ]+P Na [Na i ]+P Cl [C o ] r 4 MAP= DP + 1/3(SP-DP) Downward force x distance to elbow = Upward force x distance to elbow 1. Which of the following is TRUE regarding Homeostasis: a. Ambient temperature is held constant b. Nothing ever changes c. Exact setpoints are maintained in the body without any variation despite changing conditions d. The body’s internal environment is maintained within narrow limits despite changing conditions e. A change in a setpoint always indicates illness 2. When the uterus begins contracting due to a signal from a mature fetus, this is sensed by stretch receptors and sent to the mother’s hypothalamus, which causes oxytocin to be released from the pituitary gland, which enhances contractions. This homeostatic mechanism is best described as: a. Negative feedback b. Positive feedback c. Feedforward regulation d. Equilibrium regulation e. Both b and c For questions 3-5 a term regarding ligands and their protein binding sites is given. Match the correct definition with the terms below. (1/2 pt each) 3. Affinity 4. Saturation 5. Allosteric a. When more than one ligand can bind to the same binding site, ligands compete for sites. b. This type of modulator forms a non-covalent bond with a protein causing a conformational change in the functional site. c. This type of modulator requires a chemical reaction to form a covalent bond of charged chemical groups with a protein, thereby causing a conformational change in the functional site. d. Strength of ligand-protein binding. e. The fraction of total binging sites that are occupied at any given time.
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IB132 Summer 2009 Name: ___________________________________ Human Physiology Midterm 2 6. A cell-cell junction that is typically found in the intestine and which forces polar molecules to travel though epithelial cells rather than between cells, and a cell-cell junction that links the cytosol of adjacent cells through small diameter channels allowing molecules or signals to be exchanged is describing: a. Desmosomes and gap junctions, respectively. b.
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This note was uploaded on 12/29/2010 for the course IB 132 taught by Professor Brooks during the Summer '08 term at University of California, Berkeley.

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IB 132 - Summer 2009 - Mau - Midterm 1 - IB132Summer2009

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