Lect11 Skin&Nervous System Diseases

Lect11 Skin&Nervous System Diseases - Chapter 19...

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Chapter 19 – Microbial Diseases of the Skin Structure of the skin Normal microbiota of the skin Bacterial diseases of the skin Viral diseases of the skin
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Structure of the skin
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Structure of the skin Epidermis – surface layer of skin Dermis – 2 nd , deeper layer of skin Contains nerves, blood vessels, lymphatic vessels Adheres to hypodermis Sweat glands release sweat Provides water, nutrients for microbial growth Sebaceous glands secrete sebum Glands provide passage for bacteria to reach deeper tissues
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Normal Skin Flora Malassezia – lipophilic yeasts Digest sebum Can be opportunists Staphylococcus and Micrococcus – aerobic Gram(+) Salt-tolerant Prevent colonization by other pathogens May be opportunists Staphylococcus epidermidis Diptheroids – pleomorphic Gram(+) bacilli Generally non-pathogenic Produces acid → lowers skin pH Propionibacterium acnes
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Bacterial Diseases of the Skin
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Diseases caused by Staphylococcus aureus Skin diseases: folliculitis, sty, furuncle, carbuncle Scalded skin syndrome Impetigo Toxic shock syndrome Bacteremia Endocarditis Pneumonia Food poisoning
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Folliculitis Infection of a hair follicle – base of follicle becomes red, swollen and pus-filled Pimple Sty – occurrence at base of eyelid Furuncle (boil) – painful, raised nodular extension of folliculitis Carbuncle – coalescence of several furuncles Staphylococcus aureus Staphylococcus epidermidis
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Staphylococcus aureus Epidemiology Most often found in infants, elderly, immunocompromised Direct contact transmission Indirect contact through fomites Prevention and Treatment
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This note was uploaded on 12/29/2010 for the course BIOL 210 taught by Professor Gutiérrez during the Spring '10 term at Coastline Community College.

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Lect11 Skin&Nervous System Diseases - Chapter 19...

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