f04_exam_2 - Name: _ Date: _ I. (8 pts) Choose the correct...

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Name: __________________________ Date: _____________ I. (8 pts) Choose the correct answer from the list on the right. Not all answers will be used. A) light chains B) capping C) fibrous D) globular E) vitamin C F) motor G) glutamine H) collagen I) glycine J) myosin 1. The structural components of cells are ____________ proteins. 2. Connective tissues and bones contain large amounts of the protein ________. 3. Energy is converted into mechanical work by ________ proteins. 4. The amino acid essential to the collagen triple helix is ________________. 5. The expansion of microfilaments is limited by ________ proteins. 6. The peptides that coil around the neck of muscle mysoin are called ________. 7. The structure of kinesin is very similar to the structure of the protein ________. 8. The hydroxylation of proline in collagen requires ________________. Page 1
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II. (12 pts, 1.5 each) Choose the one alternative that best completes the statement or answers the question. 9. The protein actin can exist in two forms: A) globular and polymeric B) globular and deactivated C) GTP and ATP binding forms D) all of the above. E) none of the above. 10. The bundles of myosin tails in a muscle cell are called: A) cytoskeleton B) thick filaments C) thin filaments D) all of the above. E) none of the above. 11. Coiled coils are part of the structure of which of the following proteins? A) keratin B) mysoin C) kinesin D) B and C E) A, B, and C 12. ( 5-21) The bacteria, Clostridium perfringens, that is the causative agent of gas gangrene secretes an enzyme that cleaves the peptide bond ----X---Gly---Pro---Y--- between the Gly and Pro residues. Why is this enzyme particularly damaging to animal tissues and does not affect the bacteria? A) Animal tissues do not contain an inhibitor of the protease and bacteria have an inhibitor. B) The enzyme only works when oxygen is absent. C) Animal tissues are rich in collagen. D) The bacterial proteins are very poor in gly and pro residues. E) none of the above Page 2
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13. (5-33) The papaya plant contains the enzyme papain which is a collegenase. Which of the following are true A) Papain in the primary constituent of meat tenderizer B) Addition of fresh papaya to a Jello salad helps to make it gel faster C) Addition of cooked papaya to a Jello salad makes it gel slower D) Addition of fresh papaya prevents the Jello salad from gelling E) A and D 14. Microtubules and microfilaments are similar in what ways: A) they cannot disassemble once formed B) they are both assembled from globular subunits C) they both bind XTPs D) B and C E) A and B 15. Which of the following can carry “cargo”? A) keratin B) myosin C) kinesin D) B and C E) A, B, and C 16. Tubulin is a good target for anticancer agents because A) most chemotherapies target cells with arrested cell cycles B) microtubule assembly is important in cell division C) movement of cargo is inhibited along microtubules D) all of the above E) none of the above Page 3
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III. (8pts) (8 pts) Choose the correct answer from the list on the right. Not all answers will be
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f04_exam_2 - Name: _ Date: _ I. (8 pts) Choose the correct...

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