Chapter 4 slide 22-42[1]

Chapter 4 slide 22-42[1] - b. Deregulated myc behavior is...

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1. What is true about src gene and cDNA? a. They are both potent pro-proliferative gene capable of transforming cells b. They are both well known cellular proto-oncogenes in eukaryotes c. Reverse transcriptase plays a crucial role in both src and cDNA development d. For a purified protein sample of src , fluorescent in-situ hybridization (FISH) is a suitable method to detect its deregulated activity e. both c and d 2. Gleevec is… a. a drug invented specifically to inhibit chromosomal translocation seen in Burkitts Lymphoma b. a specific anti-cancer drug that destroys cancer cells, but not normal cells c. an example of a fusion protein d. a drug made to treat cancers caused by DNA viruses such as human papilloma virus (HPV) and cervical cancer e. none of the above 3. Which of the following is NOT true of myc ? a. It is a potent transcription factor that promotes cell growth
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Unformatted text preview: b. Deregulated myc behavior is seen in Burkitts Lymphoma c. Reciprocal translocation of myc between chromosome 9 and 22 are responsible for triggering the formation of a fusion protein in chronic myelogenous leukemia (CML) d. Only deregulated myc can stimulate the pro-proliferative response in cells e. both c and d 4. Which of the following is NOT true? a. People in Africa are more susceptible to Burkitts Lymphoma b. Microarrays has allowed the scientists to exactly locate where the oncogene is located by comparing the gene expressions between a normal gene and a oncogene. c. Amplified genes do not necessarily mean that they are over-expressed d. Amplicons can be identified through a process known as comparative genome hybridization (CGH) e. All of the statements above are true 1 2 3 4...
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This note was uploaded on 01/04/2011 for the course BIO 314 taught by Professor Erster,s during the Spring '08 term at SUNY Stony Brook.

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Chapter 4 slide 22-42[1] - b. Deregulated myc behavior is...

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