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Test 1 Practice Questions

Test 1 Practice Questions - many diseases d Because it was...

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1) Which of the following do proto-oncogenes not encode for? a) Growth factor receptors that upon ligand binding stimulate the cell to undergo division b) Genes that inhibit cell division; when these genes are mutated the cell proliferates uncontrollably c) Ligands that bind to the cell’s receptors, cause a signal transduction pathway, and cause the cell to proliferate d) Proteins that enter the nucleus, bind to the DNA, and enhance transcription of genes that stimulate cell proliferation 2) Research on tumor viruses has been invaluable to biologists because: a) The majority of cancers are due to a tumor virus integrating with the host cell’s DNA and causing it to proliferate b) Although tumor viruses only cause a small minority of cancers they have led to several breakthroughs in biology such as the discovery that a virus’ DNA integrates with the host’s DNA and the discovery of retroviruses whose RNA genomes undergo reverse transcription c) Scientists were able to use the discovery of virus DNA integration to develop vaccines for
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Unformatted text preview: many diseases d) Because it was shown that tumor viruses cause cancer, isolation of cancer patients effectively stopped the spread of cancer to other people 3) Foci are: a) Monoclonal, meaning, by definition, that they stem from one cell rather than a larger number of cells b) Capable of forming a monolayer of transformed cells c) Known to occur in most organs including the liver, lungs, and pancreas d) A and C 4) Which of the following is a potential result of having a virus integrate into the hosts genome? a) The virus may integrate its genome upstream of a proto-oncogene, deregulate its expression, and cause cancer b) If the virus is used to transduce a missing gene into a stem cell, the stem cell can be introduced into the patient, thereby curing the patient of their genetic defect. c) A and B d) None of the above Answer Key: 1) B 2) B 3) A 4) C...
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