Handout - Lecture 5 - Neuromethods

Handout - Lecture 5 - Neuromethods - Neuromethods Click to...

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Click to edit Master subtitle style 1/5/11 Neuromethods
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1/5/11 Lesioning or Ablation Electrolytic Chemical – lesion Aspiration – ablation Knife –lesion Ablation is the removal of brain tissue. Ablation can be done with a scalpel, but aspiration is a more precise technique, and it allows
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1/5/11 Damage to the brain Stroke victims Head trauma Genetic abnormalities Neurodegeneration
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1/5/11 Stimulation Stimulation Pass current into area Generates action potentials Example Stimulating pre-central gyrus does what? Moveme nt
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1/5/11 Recording electrical activity Single unit recording Multiple unit recording
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1/5/11 Recording neurochemical activity Microdialysis
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1/5/11 Pharmacological methods Using drugs to understand the brain Important issues Affinity – ability to bind receptor Efficacy – ability to produce the biological response of the target Specificity – the degree to which the ligand targets the receptor of interest and not other receptors agonist: affinity and maximum efficacy
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1/5/11 Neuroimaging Computerized axial tomography aka, CT or CAT scan Contrast dye
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This note was uploaded on 01/05/2011 for the course PSY 10994 taught by Professor Ericdonny during the Spring '08 term at Pittsburgh.

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Handout - Lecture 5 - Neuromethods - Neuromethods Click to...

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