Neurodevelopmental Disorders_lecture 11

Neurodevelopmental Disorders_lecture 11 -...

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Click to edit Master subtitle style Neurodevelopmental Disorders November 4, 2008 Chapter 13 pages 407- 422
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Lecture Topics Mental Retardation Autism Spectrum Disorders Autism Attention Deficit/Hyperactivity Disorder (ADHD) Conduct Disorder
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Mental Retardation-Criteria Significantly below-average intellectual functioning IQ less than 70 Deficits in adaptive social functioning in 2 areas Communication Self-care Home living Interpersonal skills Use of community resources Ability to make own decisions Functional academic skills, leisure, work, health, and safety Onset before 18
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Classifications of Mental  Retardation Mild: 50 – 55 to 70 IQ (50-70) Moderate: 35 – 40 to 50 – 55 IQ (35-49) Severe: 20 – 25 to 35 – 40 IQ (20-34) Profound: Below 20-25 IQ AAMR attempting to shift from traditional
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Etiology Of Mental Retardation Around 25%, known biological cause Genetic/Chromosomal Anomalies Trisomy 21 aka Down Syndrome (47 chromosomes) Down Syndrome is usually caused by the presence of an extra 21st chromosome, and typically results in individuals with IQs in the 40-55 range, although some are less impaired. Fragile X Syndrome Recessive-Gene Diseases Phenylketornuia (PKU) Phenylketornuia is due to an inherited inability to metablolize the amino acid phenylalanine; the excess phenylalanine
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Normal Karyotype
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Karyotype with Trisomy 21
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Etiology Of Mental Retardation Infectious Diseases In utero- Rubella, Syphilis, HIV After birth- Encephalitis, meningococcal meningitis, hydrocephalus Accidents Leading cause of mental retardation before the age of one. Environmental Hazards Lead, mercury, etc.
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Prevention of Mental Retardation Difficult until determine causes Likelihood of reproductive cell containing extra copy of chromosome 21 increases as women age
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This note was uploaded on 01/05/2011 for the course PSY 10994 taught by Professor Ericdonny during the Spring '08 term at Pittsburgh.

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Neurodevelopmental Disorders_lecture 11 -...

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