ETX 135 Quiz 2 ANSWER KEY

ETX 135 Quiz 2 ANSWER KEY - ETX 135 Quiz #2 ANSWER KEY...

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ETX 135 Quiz #2 ANSWER KEY Question 1. (6 points) Name three possible points of departure. Provide a brief definition for each. NOAEL – No Observed Adverse Effect Level – the highest dose at which no statistically significant adverse effects were observed in a study. LOAEL – Lowest Observed Adverse Effect Level – The lowest dose at which statistically significant adverse effects were observed in a study. Benchmark Dose – The 95% lower confidence limit on the calculated or modeled dose that causes a specified response rate (e.g., 5%)based on dose-response information from a study. Question 2. (6 points)Why is the benchmark dose method preferred over the traditional NOAEL approach? Give at least 3 reasons. Uses all the dose-response information in a study Avoids arguments over whether a NOAEL is really a NOAEL Avoids the use of a LOAEL and associated uncertainty factor. You know where you are on the dose-response curve – you set the level. Choice of investigator drives the POD with the NOAEL/LOAEL approach.
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ETX 135 Quiz 2 ANSWER KEY - ETX 135 Quiz #2 ANSWER KEY...

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