week 8 objectives

week 8 objectives - is and its role in replication. Oct 30...

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Biology 112: Unicellular life. Drs. Kion, Spiegelman, Taylor Week 8 Readings Freeman 14.2-14.5, 16.6 Brock 11.4-11.8 (e-text chapter 8) Online Pre-Class Assignment - Week 8 Due by 8am on Oct 26 th PeerWise question submission on Week 8 material Group B – due by 8am on Nov 2 nd PeerWise question feedback All students must answer at least one question and leave feedback during Week 8 Oct 26 th Invention Activity Oct 28 th DNA Replication Discussion topics: s Mechanism of replication s DNA polymerase s Replicating the ends of DNA Related learning objectives: s Explain the logic of the process of DNA replication including how the cell solves the problems of: o Separating the DNA strands. o Replicating both strands simultaneously. o Providing primers for laggings strand DNA synthesis. o Replicating the ends of the DNA. s Explain the function of the following enzymes: o DNA Polymerase III o DNA Gyrase (topoisomerase) o Helicase/Primase o Single Strand Binding Protein o DNA Polymerase I o DNA Ligase s Explain what an Okazaki fragment
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Unformatted text preview: is and its role in replication. Oct 30 th Mutations Discussion topics: s Types of mutations s Causes of mutations s Effects of mutations on proteins and gene regulation s Locating mutations Related learning objectives s Define the different types of changes to DNA sequence. s Predict effects of mutations in different locations of expression units in bacteria. s Describe the origin of mutations through errors in replication, and Biology 112: Unicellular life. Drs. Kion, Spiegelman, Taylor damage to the DNA by UV light and selected chemical mutagens. s Describe mechanisms that cells have for correcting damage to DNA (UV damage, nucleotide excision repair). s Estimate rates of mutations given simple examples. s Devise procedures for finding mutations in bacteria given simple examples. s Describe the effect mutations can have on the genotype and phenotype of a cell. Follow-up practice questions Available online by Oct 31 st...
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This note was uploaded on 01/06/2011 for the course BIO 112 taught by Professor Taylor during the Fall '09 term at UBC.

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week 8 objectives - is and its role in replication. Oct 30...

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