Lecture 8 - Recognition DNA-Protein

Lecture 8 - Recognition DNA-Protein - DNA & DNA :...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
DNA & DNA : Protein Interactions BIBC 100
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Sequence = Information Alphabet = language L,I,F,E LIFE DNA = DNA code A, T, C, G CAC=Histidine CAG=Glutamine GGG=Glycine Protein = Protein code 20 a.a. L, I, F, E N C N C LIVE EVIL
Background image of page 2
A DNA chain has polarity Just as for proteins we have N C, for DNA the base sequence is 5’ 3’ Both proteins and DNA are polymers with sequence specificity and directionality Protein: Polypeptide DNA: Polynucleotide 5’ OH unlinked 3’ OH unlinked Amino-end Carboxy-end DNA basics
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
What is a nucleotide? Nucleotide: Base + Sugar + Phosphate Nucleoside: Base + Sugar A,G,C,T ribose, deoxyribose 3 phosphates
Background image of page 4
Four kinds of bases joined to a sugar-phosphate backbone A= Adenosine (purine) T= Thymine (pyrimidine) G= Guanine (purine) C= Cytosine (pyrimidine) 2H bonds 3H bonds Length of H bond < 3Å
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Double stranded DNA Packed – right handed helical staircase (double helix) Rails: antiparallel sugar-phosphate chains Steps: Purine-Pyrimidine base pairs H-bonded Polarity: sequence 5’ 3’ direction ACG = GCA
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 20

Lecture 8 - Recognition DNA-Protein - DNA &amp; DNA :...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online