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Unformatted text preview: Homework questions analytical biochemistry 1. Which disease in newborn screening cannot be easily picked up by mass spectrometry? (answers found in Boyer) a. None. Newborns must not be screened due to ethical considerations. b. Phenylketonuria, testing circulating phenylalanine levels. c. Type I diabetes, testing circulating insulin levels. d. Maple syrup urine disease, testing leucine, isoleucine, valine circulating levels. e. Jaundice, testing circulating bilirubin a heme catabolite. 2. What is the correct definition of mass spectrometry? (answers found in Boyer) a. Measuring masses using spectrometers, e.g. certain prisma b. Connecting separation instruments (chromatography) to devices that respond to mass differences c. Analyzing mass-to-charge ratios in samples d. Utilizing high vacuum turbopumps to generate conditions at which samples ionize e. A collection of tools suitable to determine masses of samples 3. Which tools are most suitable to detect differences in hydroxy-methylglutarate levels (HMG) in...
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This note was uploaded on 01/08/2011 for the course BIS 103 taught by Professor Abel during the Winter '08 term at UC Davis.
- Winter '08