Fiehn BIS103 lecture 10_fall 2010

Fiehn BIS103 lecture 10_fall 2010 - Overview so far....

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1 Overview so far…. Amino acids Amino acids Galactose Mannose Fructose PDH Glycogen Lipids gluconeogenesis Fatty acid degradation and synthesis are linked to AcetylCoA
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2 Lipid metabolism Some major lipid classes
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3 Stored lipids are catabolized by phospholipase A2 Food lipids are incorporated into chylomicrons for transport to organs
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4 Lipoproteins transport lipids through the body ‘Chylomicrons’ are clearly visible after a meal !
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5 Along transport, lipoproteins change composition Along transport, lipoproteins change composition
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6 The liver is the organ of lipid metabolism Fatty acid degradation and synthesis are spatially separated
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7 Fatty acid β -oxidation releases energy through the TCA cycle and the electron transport chain Fatty acids need activation by CoASH for degradation
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8 Fatty acids need activation by CoASH for degradation Transport of fatty acid into mitochondria
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9 Each round of β -oxidation releases acetyl- CoA and a fatty acid that is 2 carbons shorter Fatty acids undergo β -oxidation Voet, Voet & Pratt
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This note was uploaded on 01/08/2011 for the course BIS 103 taught by Professor Abel during the Winter '08 term at UC Davis.

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Fiehn BIS103 lecture 10_fall 2010 - Overview so far....

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