Fiehn BIS103 lecture 16_fall 2010

Fiehn BIS103 lecture 16_fall 2010 - Regulation of...

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1 Regulation of metabolism hormones are produced in a variety of different organs Classes of hormones
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2 Regulation of metabolism many hormones travel in the blood stream but are perceived by cell specific membrane-bound proteins (receptors) Glucagon is also a peptide hormone derived from a larger polypeptide Epinephrine is a catecholamine preproglucagon convertase2 tyrosine b L-dopa b dopamine b norepinephrine b epinephrine tyr hydroxylase decarboxylase β -hydroxylase phenylethanolamine N-methyltransferase
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3 Hormones regulate the level of metabolism both antagonists glucagon and insulin are produced in the pancreas Insulin production in pancreatic β -cells is ready-to-go Langerhans islets
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4 Hormones regulate the level of metabolism epinephrine (adrenaline) and glucagon prepare for action insulin activates glycogen synthesis and lipogenesis Hormones regulate the level of metabolism epinephrine (adrenaline) and glucagon prepare for action insulin activates glycogen synthesis and lipogenesis
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Fiehn BIS103 lecture 16_fall 2010 - Regulation of...

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