Microbial Physiology notes lec25 11-24-10 table

Microbial Physiology notes lec25 11-24-10 table - Protein...

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Protein Secretory Pathways (PSP) in Living Organisms SP # Type Name (Pathway) Bact Arch Euk # Prots Energy I ABC ATP-binding cassette translocase + + (+) 3-4 ATP IIa Sec General secretory translocase + + + ~12 Can use either GTP or ATP w/ equal efficiency + also takes advantage of pmf It looks like that ATP/GTP fxns in the initial step in protein insertion or secretion this system inserts proteins in the membrane and also translocates proteins across its the SecY protein that is responsible for both fxns SecY is an alpha helical type pore that can translocate proteins across the membrane, or it can insert proteins into the membrane so this protein would have to have a channel through the whole membrane (this allows them to secrete proteins into the external environment) and it has to have a gated pore that goes the entire membrane that can be open/close and the pore that opens up and allows the protein strand that is w/in the pore complex to be able to diffuse out and into the membrane so it has 2 gates, 1 for
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This note was uploaded on 01/09/2011 for the course BIMM 130 taught by Professor Saier during the Fall '10 term at UCSD.

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Microbial Physiology notes lec25 11-24-10 table - Protein...

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