Exam 1 Learning Objectives

Exam 1 Learning Objectives - Learning Objectives, Chapters...

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Learning Objectives, Chapters 1 to 3, Rubin’s Essentials of Pathology, 5 th edition Chapter One, Cell Injury 1. Describe the four basic mechanisms by which the plasma membrane protects the metabolic balance of a cell. Ion pumps Anchoring point Receptors help determine how cell interacts with external environment 1. Compare/contrast hypertrophy with hyperplasia. Cite an example of each. Hypertrophy – increase in cell size… example: cardiac muscle; hyperplasia – increase in cell number… example: skin 1. Describe how metaplasia and dysplasia differ. Metaplasia – one normal type of cell changes into a different type of normal cell Dysplasia – abnormal growth 1. Profile the process of hydropic swelling. Cite an example. Ion pumps shut down, usually caused by ischemia… that allows sodium (water follows… potassium leaks out) to get into the cell… renal tubule cells in ATM 1. Construct a case for cell injury caused by any two of the reactive oxygen species (ROS). Cite the origin and role of each of the ROS you select and how each damages a cell. Hydroxyl radicals Chronic granulomatous disease 1. Discuss how intracellular storage of a substance may be considered “abnormal”. Cite an example. Iron
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This note was uploaded on 01/09/2011 for the course PATH 128 taught by Professor Reisner during the Fall '10 term at UNC.

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Exam 1 Learning Objectives - Learning Objectives, Chapters...

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