Introduction to Genetic Analysis 14

Introduction to Genetic Analysis 14 - 13 1.4 Model...

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Unformatted text preview: 13 1.4 Model organisms Gene P Chromosomal DNA Total cut DNA Southern blot Blot probed with cloned gene P (labeled) Blot probed with cloned gene P (labeled) Blot probed with antibody to protein P (labeled) Northern blot Western blot Total mRNA Total protein mRNA to be detected Cut DNA fragment to be detected Protein product P to be detected (a) Fraction- ation Gene P fragment Gene P mRNA Gene P protein (b) (c) Electro- phoresis species. Even for the features that vary, however, that variation is always between major groups of living forms, so that we do not have to investigate the basic phenom- ena of genetics over and over again for every species. In fact, all the phenomena of genetics have been investi- gated by experiments on a small number of species, model organisms, whose genetic mechanisms are com- mon either to all species or to a large group of related organisms. Lessons from the first model organisms The use of model organisms goes back to the work of Gregor Mendel, who used crosses between horticultural varieties of the garden pea,...
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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