Introduction to Genetic Analysis 66

Introduction to Genetic Analysis 66 - 44200_02_p27-72...

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65 Problems pedigree as possible. (Invent your own defned allele symbols.) c. Consider the Four unaFFected children oF parents III-4 and III-5. In all Four-child progenies From par- ents oF these genotypes, what proportion is expected to contain all unaFFected children? 15. ±our human pedigrees are shown in the accompany- ing illustration. The black symbols represent an ab- normal phenotype inherited in a simple Mendelian manner. a. Draw the relevant parts oF the pedigree, and show all the genotypes as completely as possible. b. What is the probability that the cousins’ frst child will have Tay-Sachs disease, assuming that all people who marry into the Family are homozygous normal? 17. The accompanying pedigree was obtained For a rare kidney disease. a. ±or each pedigree, state whether the abnormal condition is dominant or recessive. Try to state the logic behind your answer. ±or each pedigree, describe the genotypes oF as many persons as possible.
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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