Introduction to Genetic Analysis 68

Introduction to Genetic Analysis 68 - 44200_02_p27-72...

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67 Problems winged male is crossed with a homozygous wild- type female, what ratio of normal to small-winged Fies can be expected in each sex in the ± 1 ? If ± 1 Fies are intercrossed, what ± 2 progeny ratios are ex- pected? What progeny ratios are predicted if ± 1 fe- males are backcrossed with their father? 26. An X-linked dominant allele causes hypophospha- temia in humans. A man with hypophosphatemia marries a normal woman. What proportion of their sons will have hypophosphatemia? 27. Duchenne muscular dystrophy is sex-linked and usually affects only males. Victims of the disease be- come progressively weaker, starting early in life. a. What is the probability that a woman whose brother has Duchenne’s disease will have an af- fected child? b. If your mother’s brother (your uncle) had Duchenne’s disease, what is the probability that you have received the allele? c. If your father’s brother had the disease, what is the probability that you have received the allele?
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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