Introduction to Genetic Analysis 116

Introduction to Genetic Analysis 116 - made? OUTLINE 4.1...

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115 4 EUKARYOTE CHROMOSOME MAPPING BY RECOMBINATION KEY QUESTIONS For genes on the same chromosome (known as linked genes ), can new combinations of alleles be detected in the progeny of a dihybrid? If new combinations of alleles arise, by what cellular mechanism does this happen? Can the frequency of new combinations of alleles for linked genes be related to their distance apart on the chromosome? If we do not know whether two genes are linked, is there a diagnostic test that can be
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Unformatted text preview: made? OUTLINE 4.1 The discovery of the inheritance patterns of linked genes 4.2 Recombination 4.3 Linkage maps 4.4 Using the chi-square test in linkage analysis 4.5 Using Lod scores to assess linkage in human pedigrees 4.6 Accounting for unseen multiple crossovers Chiasmata, the visible manifestations of crossing-over, photographed during meiosis in a grasshopper testis. [John Cabisco/Visuals Unlimited.] 44200_04_p115-150 3/2/04 11:53 AM Page 115...
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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