Introduction to Genetic Analysis 303

Introduction to Genetic Analysis 303 - 302 Chapter 10 •...

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Unformatted text preview: 302 Chapter 10 • Regulation of Gene Transcription CHAPTER OVERVIEW T he biological properties of each cell are largely deter- mined by the active proteins expressed in it. This constellation of expressed proteins determines much of the cell’s architecture, its enzymatic activities, its interac- tions with its environment, and many other physiological properties. However, at any given time in a cell’s life his- tory, only a fraction of the RNAs and proteins encoded in its genome are expressed. At different times, the profile of expressed gene products can differ dramatically, both in regard to which proteins are expressed and at what levels. How are these specific profiles created? The regulation of the synthesis of a gene’s transcript and its protein product is often termed gene regulation. As one might expect, if the final product is a protein (as is true for most genes), regulation could be achieved by adjusting the transcription of DNA into RNA or the translation of RNA into protein. In fact, gene regulationtranslation of RNA into protein....
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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