Introduction to Genetic Analysis 177

Introduction to Genetic Analysis 177 - 44200_05_p151-184...

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176 Chapter 5 The Genetics of Bacteria and Their Viruses Does bacterial recombination resemble eukaryote recombination? Yes, in the sense that AB can be produced from A b and a B . No, in the sense that recombination always takes place in a partial diploid (merozygote) as opposed to a true diploid. Hence the recombination is formally a double-crossover event, needed to maintain the circular bacterial chromosome intact. Do the genomes of bacterial viruses ever show recombination? Yes, if a bacterial host is infected simultaneously by two phage types, recombinant phage are found in the lysate. Do bacterial and viral genomes interact physically in any way? Yes, temperate phages can pick up bacterial genome fragments during lysis and transfer them to other bacte- ria when they reinfect. Some phages pick up only one speciFc region; others can pick up any segment that can be stuffed into a phage head. Can bacterial and viral chromosomes be mapped using recombination? Yes, all bacterial merozygotes can be used for recombi-
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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