177Solved problems1.Suppose that a cell were unable to carry out general-ized recombination (rec2). How would this cell be-have as a recipient in generalized and in specializedtransduction? First compare each type of transduc-tion and then determine the effect of the rec2muta-tion on the inheritance of genes by each process.SolutionGeneralized transduction entails the incorporation ofchromosomal fragments into phage heads, which theninfect recipient strains. Fragments of the chromosomeare incorporated randomly into phage heads, so anymarker on the bacterial host chromosome can be trans-duced to another strain by generalized transduction. Incontrast, specialized transduction entails the integra-tion of the phage at a specific point on the chromo-some and the rare incorporation of chromosomal mark-ers near the integration site into the phage genome.Therefore, only those markers that are near the specificintegration site of the phage on the host chromosomecan be transduced.
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