Introduction to Genetic Analysis 625

Introduction to Genetic Analysis 625 - 44200_19_p611-642...

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diversity. The results of both calculations are given in Table 19-6. Note that the haplotype diversity is always greater than the average heterozygosity of the separate loci, because an individual is a haplotypic heterozygote if either of its genes is heterozygous. Random mating The Hardy-Weinberg equilibrium was derived on the assumption of “random mating,” but we must carefully distinguish two meanings of that process. First, we may mean that individuals do not choose their mates on the basis of some heritable character. Human beings are ran- domly mating with respect to blood groups in this ±rst sense, because they generally do not know the blood type of their prospective mates, and even if they did, it is unlikely that they would use blood type as a criterion for choice. In this ±rst sense, random mating will occur with respect to genes that have no effect on appearance, behavior, smell, or other characteristics that directly in- ²uence mate choice.
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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