Introduction to Genetic Analysis 641

Introduction to Genetic Analysis 641 - d. The...

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Unformatted text preview: d. The Hardy-Weinberg genotypic frequencies are ( p 1 q 1 r ) 2 5 p 2 1 q 2 1 r 2 1 2 pq 1 2 pr 1 2 qr 5 0.04 1 0.09 1 0.25 1 0.12 1 0.20 1 0.30 which are precisely the observed frequencies. So it ap- pears that the population is in equilibrium. 4. In a large experimental Drosophila population, the fitness of a recessive phenotype is calculated to be 0.90, and the mutation rate to the recessive allele is 5 3 10 2 5 . If the population is allowed to come to equilibrium, what allele frequencies can be predicted? Solution Here mutation and selection are working in opposite di- rections, so an equilibrium is predicted. Such an equilib- rium is described by the formula In the present question, 5 5 3 10 2 5 and s 5 1 2 W 5 1 2 0.9 5 0.1. Hence p 5 1 2 0.022 5 0.978 q 5 5 3 10 2 5 10 2 1 5 2.2 3 10 2 2 5 0.022 q 5 s PROBLEMS B ASIC P ROBLEMS 1. What are the forces that can change the frequency of an allele in a population?...
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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