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Unformatted text preview: Deletion (c) Gain of function: hypermorphic mutation Mutant phenotype Mutant phenotype Deletion MM Gain of extra gene activity in partly compensated by deletion Gain of extra gene activity in made more severe by duplication (d) Gain of function: neomorphic mutation New mutant phenotype Deletion Novel gene activity encoded by insensitive to gene dosage of wild-type gene: All M phenotype Figure 16-22 Distinguishing various functional causes of dominant mutations. See the text for discussion. 44200_16–p521-544 3/17/04 9:12 AM Page 536...
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.
- Spring '08