34.Every mutagen produces a certain characteristictype of mutational event. Explain your answers tothe following questions:a.Would you expect hypomorphic mutations tobe more frequent among all mutations produced by base-substitution mutagens or by frameshift mutagens?b.Would you expect null mutations to be more frequent among all mutations produced by base-substitution mutagens or by frameshift mutagens?35.Neomorphic mutations can be reverted by treat-ment with standard mutagens. When the revertantsare examined, they typically turn out to be recessiveloss-of-function mutations. Explain this observation.36.You are trying to identify all mutations that affectdevelopment of the dorsal Fn in the zebra Fsh. Youdo an ±3mutagenesis analysis for recessive muta-tions that cause loss of the dorsal Fn. By recombina-tion and complementation analysis, you Fnd that 40mutations you’ve isolated represent mutations inFve genes, with 12 mutations in one gene, 10 muta-tions in each of two others, 7 mutations in a fourthgene, and only 1 mutation in a Ffth.
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