Introduction to Genetic Analysis 413

Introduction to Genetic Analysis 413 - 44200 GRIFFITHS...

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44200 24 Chapter 12 Genomics 44200 GRIFFITHS FREEM Ch-12 First Pages Sen 12-10-2003 p 24 Application File the presence of conserved sequences can provide infor- mation on the evolution of entire chromosomes. Thus, human chromosome 7 appears to be composed of sequences that are largely conserved in the mouse genome (Figure 12-26), but the mouse sequences homo- logous to human chromosome 7 are split into 19 blocks located on six different chromosomes. Thus comparative genomics reveals that chromosomal rearrangement, to be fully discussed in Chapter 15, is a key mechanism in chromosomal evolution. The process of evolution can be considered the longest-term genetic experiment that we have available to us. We are just learning to use the power of comparative genomics to help decipher the in- formation encrypted in a genome. The effects of genomics on biological research Even though genomics as a technology and an approach is not even 20 years old, it has already become an aca- demic household word. The analysis of whole genomes
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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