34 Chapter 12 • Genomics 44200 GRIFFITHS FREEM Ch-12 First Pages Sen 12-10-2003 p 34 Application File EXPLORING GENOMES A Web-Based Bioinformatics Tutorial Introduction to Genomic Databases Where does a researcher turn to find information about a gene? Integrated genetic databases are maintained by a number of private and government organizations. In the first Genomics tutorial at www.whfreeman.com/iga, you will be introduced to the resources available through the National Center for Biotechnology Information (NCBI) in Washington, D.C. Learning to Use ENTREZ The ENTREZ program at NCBI is an integrated search tool that links together a variety of databases that have different types of content. In the Genomics tutorial at Web site www.whfreeman.com/iga, we will use it to look up the dystrophin gene associated with muscular dystrophy and find research literature references, the gene sequence as well as conserved domains, the equivalent gene from a variety of organisms other than human, and the
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