Introduction to Genetic Analysis 437

Introduction to Genetic Analysis 437 - 436 Chapter 13 The...

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Unformatted text preview: 436 Chapter 13 The Dynamic Genome: Transposable Elements DNA transposons Some mobile elements found in eukaryotes appear to transpose by mechanisms similar to those in bacteria. As we saw in Figure 13-12, for IS elements and transposons, the entity that inserts into a new position in the genome is either the element itself or a copy of the element. Ele- ments that transpose in this manner are called class 2 elements or DNA transposons. The first transposable elements discovered by McClintock in maize are now known to be DNA transposons. However, the first DNA transposons to be molecularly characterized were the P elements in Drosophila. P ELEMENTS Of all the transposable elements in Drosophila, the most intriguing and useful to the geneti- cist are the P elements. These elements were discovered as a result of studying hybrid dysgenesis a phenome- non that occurs when females from laboratory strains of Drosophila melanogaster are mated with males derived from natural populations. In such crosses, the laboratory stocks are said to possess an...
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