Introduction to Genetic Analysis 476

Introduction to Genetic Analysis 476 - 44200_14_p451-480...

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475 14.4 The mechanism of meiotic crossing-over a inner chromatid A inner chromatid Double-strand break and erosion of ends Broken end invasion and loop formation Migration of loop and synthesis Gap-filling and union of free ends Breakage and reunion at 2 and 3 Holliday structure 5a Breakage and reunion at 2 and 4 5b Repair to Full double-helical crossover This will be a 6:2 octad. This will be a 6:2 octad. If no / repair, a 5:3 octad would result. Noncrossover outcome a A A A a A A A Heteroduplex with mismatch A A A 2 1 3 2 44 1 3 A A A A A a a A A a DNA double helix 3 ' ends DNA double helix
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This note was uploaded on 01/10/2011 for the course BIOL BIOL taught by Professor Johnson during the Spring '08 term at Aberystwyth University.

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