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EBME_410_molecular_imaging

EBME_410_molecular_imaging - In Vivo Cellular and Molecular...

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Page 1 In Vivo In Vivo Cellular and Molecular Cellular and Molecular Imaging using MR and Bioluminescent Imaging Bioluminescent Imaging David L. Wilson Departments of Biomedical Engineering Departments of Biomedical Engineering and Radiology and Radiology Case Western Reserve University 2 Applications in Humans Applications in Humans Detection of disease Staging of disease Image guided therapies Assessment of therapy 3 The New Patient 23 million laboratory mice in 1998 Some estimate 100,000 currently at Case 1,000 hospital beds at University Hospitals of Cleveland 4 Applications in Mice Applications in Mice Develop methods for disease detection, staging, and assessment of therapy Phenotype genetically modified mice Characterize mouse models of disease; e.g., cancer Assess of drug and gene therapies Use as a tool to discover biology Etc.
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