Gero 310 F'09 urinary

Gero 310 F'09 urinary - Normal function, physiology and...

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Unformatted text preview: Normal function, physiology and anatomy • functions Urinary system 1. Waste removal- byproducts of cellular metabolism passed to blood, removed by urinary system- wastes include urea, ammonia (protein/amino acid breakdown), uric acid (nucleic acid breakdown), creatinine (from muscle cells) 2. Osmotic and blood pressures- regulate water levels in blood which affects blood pressure and fluid content in tissues 3. Ion concentrations- alter retention/absorption of different materials as needed- regulated ions including Ca ++ , Na + , K + , Mg ++ Chp 12 Chp 12 • anatomy and physiology * process of action = filtering- primary filtering organ is kidney- kidney acts as a specialized filtering system- kidney filters like a collander: retains good material and lets out bad stuff (e.g., dirt) and excess (e.g., water)- blood is the filtered material QuickTimeª and a TIFF (Uncompressed) decompressor are needed to see this picture. encognitive.com * kidney anatomy- outer region called cortex- inner region called medulla- kidneys organized into functional units called nephrons- ~1 million nephrons per kidney- blood flows into kidney via the renal artery- renal artery flows directly from aorta- blood flows through kidney, is filtered, then exits via the renal vein- nephrons consist of several anatomical components: * glomerulus * Bowman’s capsule * renal tubule : three sections: 1. proximal tubule 2. loop of Henle 3. distal tubule • nephron performs four basic functions : 1. filtration of blood 2. reabsorption of desirable components * esp. glucose, water, amino acids, ions 3. active secretion of unwanted components * including excess ions, drug clearing 4. collection & excretion of urine * urine : waste products & water How is filtration accomplished ? • arterioles branched from the renal artery terminate in capillaries called glomeruli • much of blood contents passes through glomeruli into kidneys at site called Bowman's capsule- many blood components retained by glomeruli • from Bowman's capsule, blood filtrate passes into the proximal renal tubule • desirable components of blood filtrate reabsorbed and returned to blood- water, ions, etc, • distal tubule particularly important in water reabsorption- site of action of anti- diuretic hormone (ADH)- recall that ADH released by pituitary under hypo- thalamic control to increase water content of blood • undesirable and waste...
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This note was uploaded on 01/16/2011 for the course GERO 310 taught by Professor Davies during the Fall '09 term at USC.

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Gero 310 F'09 urinary - Normal function, physiology and...

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