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Biol110-10-Lecture 1-Intro

Biol110 10 lecture 1 intro

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Unformatted text preview: Biol110 Cell Biology-Fall Quarter 2010 Textbook is Alberts et al 5th edition, 2008, “Molecular Biology of the Cell” Biol110-sections 206 Biol110 students, but only 176 enrolled in sections- please enroll Movie: “The inner life of the cell” http://www.youtube.com/watch?v=mbcWGU8fpxA Biol110-10-Assigned Reading from Alberts et al 5th Edition Assigned reading covered in the Midterm exam: Chapter 8 Chapter 9 Chapter 10 Chapter 11 Chapter 12 Chapter 13 pgs 501-532 all all pgs 651-682 pgs 695-719 & 723-745 pgs 749-754 & 760-762 & 771-779 Assigned reading covered in the Final exam: Chapter 13 all Chapter 15 pgs 879-916 & 921-931 Chapter 16 pgs. 965-1041 Chapter 17 all Chapter 19 pgs 1131-1155; 1158-1172 Why study Cell Biology? Life Disease Medicines Curiosity Eukaryotes are highly diverse A protozoan (Didinium) eating another Bars 10 µm euglenoid dinoflagellate B cells T cells ciliates amoeba heliozoan There are three basic kinds of cells Figure 1-21 Molecular Biology of the Cell, Fifth Edition Model organisms used to study cell biology: E. Coli (bacteria) S. cerevisiae (budding yeast) A. thaliana (plant) X. laevis (frog) C. elegans (nematode/worm) Drosophila (fruit fly) Mouse Human somatic cell-lines Human embryonic stem cells E. Coli is a simple prokaryotic cell Vibrio cholerae Other prokaryotes… Major features of eukaryotic cells Modern eukaryotic cells evolved from a symbiosis Evolution from anaerobic to aerobic (1.5 billion years ago) Evolution from aerobic to photosynthetic by engulfing a cyanobacteria (plants and algae) Budding yeast (Saccharomyces cerevisiae) is a simple eukaryotic cell Arabidopsis thaliana: a model plant A single cell from a leaf The oocytes of Xenopus laevis (frog) are large (1 mm) and contain all materials needed to build 1 million cells Nematode (Caenorhabditis elegans) is a simple animal (these survived the Space Shuttle crash) Fruit flies are simple animals that can be manipulated easily through genetics antennopedia Mice are very similar to humans How are cells studied...
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