Lecture3 - Last time: Amino Acids: -basic chemical...

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Last time: Amino Acids: -basic chemical structure -peptide bond -building blocks of protein -sequence -linear polymer -spatial configuration -secondary structure, part I -R groups
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In an amino acid with an R-group that consists of 4 atoms, how many atoms are their in total? A. 11 B. 12 C. 13 D. 14 E. 15 What if the pH is 10? What if the pH is 1?
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Concepts: Tertiary structure- •secondary structure elements •secondary structure prediction •topology •loops •folds, structural motifs •sequence comparison •domains •linkers
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Beta sheets => beta strands next to each other
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Turns - flipping the direction of the chain
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R- groups
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R- groups The following amino acids are achiral: a. none b. proline c. glycine d. lysine
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R- group classification:
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R- group classification: alaphatic => non-polar , hydrophobic
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hydrophobic effect:
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R- group classification: aromatic => non-polar , hydrophobic
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UV absorbance by proteins:
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R- group classification: acidic => polar , negatively charged amides => polar, uncharged
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basic => polar, positively charged
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This note was uploaded on 01/17/2011 for the course BIOC 100A taught by Professor Harrynoller during the Fall '10 term at University of California, Santa Cruz.

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Lecture3 - Last time: Amino Acids: -basic chemical...

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