Lecture7

Lecture7 - 1 Nucleic Acids: Chemical structure: Bases,...

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1 Nucleic Acids: Chemical structure: Bases, sugars, phosphates Nucleotides Base-pairing DNA helix Information content DNA topology: link, twist, writhe, supercoil
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2 How many carbons in a ribose? A. 3 B. 4 C. 5 D. 6 The phosphate is attached to the: A. 1' position B. 2' position C. 3' position D. 4' position E. 5' position The ____ position is deoxy in DNA A. 1' position B. 2' position C. 3' position D. 4' position E. 5' position The base is attached to the: A. 1' position B. 2' position C. 3' position D. 4' position E. 5' position
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4 During DNA polymerization- the nucleophile is A. alpha phosphate B. beta phosphate C. gamma phosphate D. 2' OH E. 3' OH F. H 2 O the leaving group is A. alpha phosphate B. beta phosphate C. gamma phosphate D. 2' OH E. 3' OH F. H 2 O Nucleotide phosphate nomenclature:
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6 The bases: 9 6 2 adenine 9 6 2 guanosine
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7 The bases: 1 4 3 5 2 cytosine uracil 1 4 3 5 2 thymine 1 4 3 5 2
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8 base modifications:
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9 Tautomer
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10 Base pairs: H- bonds are formed between A. A9-T4, A1-T3 B. A3-T3, A2-T4 C. A6-T4, A1-T3 D. A2-T3, A1-T2
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Lecture7 - 1 Nucleic Acids: Chemical structure: Bases,...

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