Problem_set_1

Problem_set_1 - BIS104-002 Winter 2010 Problem Set I...

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BIS104-002 Winter 2010 Problem Set I “Due” Jan 13. This problem set will not be collected, but you should do it before looking at answers. Answers will be posted on Jan 15. 1-3. In studying tumor cells, you isolate gene X that causes protein Q to become tyrosine phosphorylated (the addition of a phosphate group to a tyrosine). You isolate a homozygous null mutation in gene X and now find that protein Q is not tyrosine phosphorylated. Furthermore, the tumor cells are now behaving more like normal cells. 1. You conclude the following: A. Gene X is sufficient for phosphorylation of Protein Q B. Gene X is necessary for phosphorylation of Protein Q C. Gene X is necessary and sufficient for phosphorylation of Protein Q 2. If you concluded that Gene X is necessary, describe an experiment to test whether Gene X is sufficient. If you concluded that Gene X is sufficient, describe an experiment to test whether Gene X is necessary. 3. In addition, you can conclude the following about gene X from the tumor cells:
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Problem_set_1 - BIS104-002 Winter 2010 Problem Set I...

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