Lect9-KR - Break on through to the other side: crossing the...

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Break on through to the other side: crossing the cytoplasmic membrane PMB/MCB112 September 20, 2010
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Lipid bilayer construction 8 nm Mg 2+ and Ca 2+ help to stabilize the membrane by making ionic bonds with negatively charged head groups
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Cytoplasmic membrane phospholipids R groups are fatty acids Linked to glycerol via ester bond Phosphatidyl ethanolamine Phosphatidyl glycerol Cardiolipin, or diphosphatidylglycerol
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Rigid planar molecules stabilize the membrane and make it less fluid Eukaryotes have cholesterol Bacteria have hopanoids such as diploptene Some bacteria secrete pore- forming toxins that bind to the cholesterol in eukaryotic cell membranes, but do not bind to their own hopanoids!
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Prokaryotic cytoplasmic membranes contain more DIFFERENT proteins than the cytoplasmic membranes of eukaryotes 10-20% of total cell protein resides in the cytoplasmic membrane Proteins have varying degrees of lateral mobility
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Functions of cytoplasmic membrane Electron transport chains are in the cytoplasmic membrane. In eukaryotes, this occurs in the mitochondrial inner membrane. Permeable to water, CO
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This note was uploaded on 01/19/2011 for the course C 112 taught by Professor Ryan during the Fall '10 term at University of California, Berkeley.

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Lect9-KR - Break on through to the other side: crossing the...

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