Lect18-KR

Lect18-KR - Lifestyles of the Small and Numerous PMB/MCB...

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
Lifestyles of the Small and Numerous PMB/MCB 112 October 13, 2010
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Endospore formation or sporulation by Gram positive bacteria Most endospore-forming bacteria live in the soil and sporulate when nutrients are limiting Mature spores are dormant/metabolically inactive, and resistant to heat, dessication, chemicals, UV radiation Generated by asymmetric cell division, where one cell becomes the spore and the other cell helps to build the spore and then disintegrates
Background image of page 2
How does Bacillus subtilis choose vegetative growth vs. sporulation?
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
1 Intermediate Response regulator Histidine phospho- transferase 2 3 4 Histidine kinase(s) DNA-binding Response regulator Sporulation phosphorelay KinA, KinB Spo0F Spo0B Spo0A
Background image of page 4
KinB Spo0F Spo0B Spo0A KinA, KinB histidine kinases Spo0F response regulator Spo0B histidine phosphotransferase Spo0A response regulator Spo0A binds DNA and regulates ~120 genes involved in sporulation Commitment to sporulation requires high levels of Spo0A~P DNA damage GTP RapA Cell
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/19/2011 for the course C 112 taught by Professor Ryan during the Fall '10 term at Berkeley.

Page1 / 9

Lect18-KR - Lifestyles of the Small and Numerous PMB/MCB...

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online