Lecture 2 DNA Structure and Replication

Lecture 2 DNA Structure and Replication - Announcements...

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1 Announcements Lecture 2 No I-clickers You can record the lectures Website for Professor Yi portion of class http://sites.google.com/site/biosci97/ Lectures and Quake article available on Lectures page http://sites.google.com/site/biosci97/lectures Problems and Problem answers are available on Problems page http://sites.google.com/site/biosci97/problems You have to attend the discussion section that you are registered for
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2 Human Genome contains ~23,000 genes Chromosome 21 (Mom) Chromosome 21 (Dad) CCR5 + CCR5- 32
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3 Genes Change by Mutations Mutation refers to any heritable change in a gene Generates diversity Change alters DNA sequence Any mutation that alters the amino acid sequence of a protein can impair its function Wild-type represents the “natural” or “common” gene (or protein or organism) Mutant represents gene (or protein or organism) containing a mutation
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4 DNA Structure and Replication Lecture 2 Fall 2010
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5 Sample Question (Lecture 1) 19. A new type of bacteriophage contains RNA as the genetic material instead of DNA. Mrs. McDonald performs a Hershey-Chase experiment using this new bacteriophage. She labels the phage RNA with 32 P and the protein with 35 S. These doubly-labeled phage are used to infect bacteria and then the mix is placed into the blender so that the phage heads are separated from the infected cells. The infected cells are isolated and the radioactivity in these cells counted. Which type(s) of radioactive species are observed? (A) 32 P only (B) 35 S only (C) 32 P and 35 S (D) 14 N only (E) No radioactivity is observed
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Outline Lecture 2 From Lecture 1: Genetics is about the inheritance of traits Definitions Genotype, phenotype and environment
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This note was uploaded on 01/21/2011 for the course BIO SCI 65 taught by Professor Yin during the Spring '10 term at Saint Joseph's University.

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Lecture 2 DNA Structure and Replication - Announcements...

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