Lecture 4 Central Dogma II- From RNA to Protein

Lecture 4 Central Dogma II- From RNA to Protein -...

Info iconThis preview shows pages 1–8. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Announcements Lecture 4 Exam covers Lectures 1 to 6, and associated problems and readings. Note, not all lecture material is in the powerpoint slides Lectures 5 and 6 will be posted shortly Answers to the recommended odd-numbered problems from Essential Genetics are posted on the web site We will provide the scantron cards The hourly exams from previous years are posted No make-up exams
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 The primary transcript is processed into mRNA in eukaryotes Exon 1 DNA Exon 2 Exon 3 Intron 1 Intron 2 Promoter Primary Transcript 5’ MeG cap Exon 1 Exon 2 Exon 3 Intron 1 Intron 2 AAA Transcription 5’ MeG cap Exon 1 Exon 2 Exon 3 AAA Splicing (introns spliced out) mRNA
Background image of page 2
3 Gene Expression is Regulated Gene expression is highly regulated and cell type-specific Neuron-specific proteins are made in neurons but not in neutrophils. Regulation of gene expression can occur by the regulation of transcription, splicing, or translation Much of gene regulation occurs through the regulation of transcriptional initiation by the presence or absence of tissue-specific transcription factors
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4 Sample Questions (Lecture 3) 11. The muscle creatine kinase gene is expressed in muscle cells but not liver cells. Which of the following is the most likely explanation for this tissue- specific gene expression: (A) A muscle-specific transcription factor is found in muscle cells, but not liver cells (B) A muscle-specific enhancer element is found in muscle cells, but not liver cells (C)A muscle-specific 5’ splice junction is found in muscle cells, but not liver cells (D)A muscle-specific rRNA is found in muscle cells, but not liver cells (E) A muscle-specific DNA polymerase is found in muscle cells, but not liver cells
Background image of page 4
5 Central Dogma II: From RNA to Protein Lecture 4 Fall 2010
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6 DNA to RNA to Protein
Background image of page 6
7 4-7 Basics of Genetic Code Translation : translate information from RNA (DNA) sequence to protein sequence Universal (nearly) Amino acids are coded for by
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 8
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/21/2011 for the course BIO SCI 65 taught by Professor Yin during the Spring '10 term at Saint Joseph's University.

Page1 / 25

Lecture 4 Central Dogma II- From RNA to Protein -...

This preview shows document pages 1 - 8. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online