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chapter_16_fall_2008_class - Chapter 16 The molecule of...

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Chapter 16 The molecule of inheritance - DNA
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MOLECULAR BASIS OF INHERITANCE MOLECULAR BASIS OF INHERITANCE How is genetic information stored in chromosomes? 1940’s postulated DNA over protein 1952 - ____________________ prove 1952 - ____________________ prove DNA responsible for inheritance DNA responsible for inheritance Bacteriophage virus directs bacteria to produce protein coat and virus DNA Bacterial cell lyses, new phages released
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Fig. 16.2
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Figure 16.2ax Phages – sixth edition
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Figure 16.3 The Hershey-Chase experiment: phages
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Labeled phage coat (protein) with 35 S Do infected bacterial cells became radioactive (with 35 S)? Fig. 16.4 Radioactivity _______ found in bacteria Hershey and Chase
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Fig. 16.4 Labeled phage DNA with 32 P Do infected bacterial cells became radioactive (with 32 P)? Radioactivity _________ in bacteria Hershey and Chase
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2. Discovery of the structure of DNA Structure explains how genetic information is stored and passed on “Players” in the race to discover the structure of DNA: James Watson Francis Crick Linus Pauling Rosalind Franklin Maurice Wilkins
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James Watson 1928- Francis Crick 1916 - 2004 Maurice Wilkins 1916 - 2004 Watson (U.S.) teamed with Crick while Watson (U.S.) teamed with Crick while visiting Cambridge England visiting Cambridge England Watson deduced double helix from x-ray diffraction photo Wilkins showed him
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