exam_4a - Biol 638, Exam-4 (Code-1) Biology 638...

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Biol 638, Exam-4 (Code-1) 1 Biology 638 – Biochemistry II Exam-4 (April 12, 2010) The following sequence of reactions represents the metabolism of amino groups in L-amino acids. The following three questions refer to this diagram. C 5 A 6 A 5 A 4 A 3 A 2 A 1 E 5 E 4 E 3 E 2 E 1 Urea HCO 3 - + NH 3 L-amino acid L-amino acid E 6 E 7 E 8 E 9 B 1 B 2 B 3 B 4 B 5 C 4 C 3 C 2 C 1 A 1 – A 6 , B 1 – B 5 , and C 1 – C 5 are representative chemicals, and E 1 – E 9 indicate either enzymes or reaction steps. 1 . Glutamate dehydrogenase is ______. a. E 3 b. E 5 c. E 6 d. E 7 e. E 9 2 . A 6 is _____. a. glutamine b. fumarate c. -ketoglutarate d. -ketoglutamine e. None of the above. 3 . B 4 is _____. a. glutamate b. -ketoglutarate c. aspartate d. oxaloacetate e. None of the above. 4 . Select the statement that is not true. a. A THF molecule can carry methyl group or formyl group or methylene group. b. Carbamoyl phosphate synthetase is allosterically activated by N-acetyl-glutamine. c. The PLP bound enzymes involve in a transamination and decarboxylation reactions. d. THF functions to transfer C 1 units in several oxidative states e. None of the above.
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Biol 638, Exam-4 (Code-1) 2 5 . Select the statement that is not true. a. The carbon skeleton of Ala is converted to pyruvate. b. Ammonia produced in tissues is transported to liver as the non-toxic forms, glutamine and alanine. c. Glycerate 3-phosphate is an intermediate of glycolysis and the precursor of cysteine biosynthesis. d. The carbon skeleton of Lys is composed of six carbon atoms and is converted to glucose by gluconeogenesis. e. None of the above. 6 . Select the statement that is not true. a. Sulfa drugs (antibiotics) inhibit the bacterial synthesis of THF since those are structural analogs of p -aminobenzoic acid that is a constituent of THF. b. Gln is the amino group donor in the formation of many biosynthetic products. c. High -ketoglutarate concentration activates uridylyl-removing enzyme. d. Adenylated glutamine synthetase is a less active enzyme. e. None of the above. 7 . Select the statement that is not true. a. Porphyrin is derived from succinyl-CoA and Gly. b. Pro is derived from Glu.
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This note was uploaded on 01/22/2011 for the course BIO 638 taught by Professor Arizumi,k during the Spring '10 term at Kansas.

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exam_4a - Biol 638, Exam-4 (Code-1) Biology 638...

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