DSP4 ESS2

DSP4 ESS2 - ESS 2 – 1/19/11 Lecture • Routes of...

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Unformatted text preview: ESS 2 – 1/19/11 Lecture • Routes of administration o Enternal Routes: Oral, Gastric, Rectal o Parenteral Routes: Skin (topical), Lungs (inhalation), Nasal cavity, Injection sites: • Subcutaneous (3-5min), Intramuscular (3-5min), Intravenous (15- 30sec), Intraperitoneal, Intrathecal • Pharmaceutical Characteristics of Drugs o Tablet not very fast, powder in solution may be better to quickly get rid of headache for example o Suspension example: alka seltzer in suspension of water o Excipient: carries drug or medicine into body o Coatings: may affect onset of action, gastric upset, etc. • Rate-Limiting in Pharmaceutical Phase o Tablets: Capsules (slower speed): disintegration Powders (medium speed): dissolution Suspensions & Solutions (fastest speed): absorption o Smoking is fastest route of administration for psychoactive effects o Intravenous is 2 nd , unless if injected into carotid artery • Determinants of the Pharmacokinetic Phase o Drug Absorption: Inhaling: 7-10sec Injecting: 15-30sec...
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This note was uploaded on 01/25/2011 for the course ESS 20305 taught by Professor Powell during the Winter '10 term at UCSB.

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DSP4 ESS2 - ESS 2 – 1/19/11 Lecture • Routes of...

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