Chapter_2_PP_Metabolism

Chapter_2_PP_Metabolism - chapter 2 Fuel for Exercising...

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2 Fuel for Exercising Muscle: Metabolism and Hormonal Control chapter
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What is Metabolism? Chemical reactions (rxn) in the body Purpose of chemical reactions: Extract energy (E) from nutrients Use E for work Store excess E for later use Two types of chemical reactions: Anabolic (sml molecule → lg molecule) Catabolic (lg molecule → sml molecule) Substrate – molecule in a chemical rxn Enzyme – catalyst in a chemical rxn
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Energy Originates from the sun (light energy) Photosynthesis (chemical energy) Energy metab: conversion of food to ATP Human body uses ATP to fuel work
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Adenosine Triphosphate (ATP)
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Carbohydrate (CHO) Function All dietary CHO eventually converted to … Glucose = C 6 H 12 O 6 Storage form Glycogenesis
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CHO (continued) Usable form for energy met Glycogenolysis Storage location(s) Energy yield (kcal/g) Primary nutrient used to produce ATP during … The only foodstuff that can generate ATP …
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Lipids (Fat) Function Storage form Triglyceride (TG) = 1 glycerol + 3 fatty acids TG synthesis Free fatty acid (FFA)
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Lipids (continued) Usable form for energy met Lipolysis Storage locations Energy yield (kcal/g) Primary nutrient used to produce ATP during … ATP generation rate Maximal available ATP (ATP capacity)
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Protein Function Storage Energy metabolism Gluconeogenesis (Alanine cycle) Glycogen depletion Energy yield (kcal/g)
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ATP Production We store a small amount of ATP in our cells. ATP-Producing Reactions Phosphorylation: ADP + P i + energy → ATP 1. Anaerobic metabolism The ATP-PCr system The glycolytic system (glycolysis) 1. Aerobic metabolism The oxidative systems: Krebs cycle β-oxidation Electron transport chain (ETC)
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The ATP-PCr System Immediate energy system Location Function Stored in cells: ATP Phosphocreatine (PCr)
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The ATP-PCr System (continued) Step 1: Step 2: Step 3: Summary: Creatine Kinase PCr + ADP + energy → Creatine + ATP
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The ATP-PCr System (continued)
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The ATP-PCr System (continued) Although ATP is being used at a very high rate, the energy from PCr is used to resynthesize ATP, preventing the ATP level from decreasing. At exhaustion, both ATP and PCr concentrations are low.
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Chapter_2_PP_Metabolism - chapter 2 Fuel for Exercising...

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