Discussion Section michelle wk 4

Discussion Section michelle wk 4 -...

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BICD 100- GENETICS (Ghiara) Spring 08 TA: Michelle Salcedo [email protected] Week 4 Errors in Genetic Material Separation Aneuploidy o Definition = an increase or decrease in number of one chromosome. o Cause   Non-disjunction Non-disjunction  = when either the sister chromatids (in mitosis or  meiosis II) or homologous pairs (in meiosis I) do not separate.  A random event If happen in gametes   then half of the daughter cells of that  particular gamete has this mistake   affects next generation (the  offspring) * non-disjunction occurring in meiosis II If happen in mitosis   then all daughter cells of that particular cell  has this mistake   affects the region of where that cell is growing  (like a certain area on your skin or organ) Why is it not a big consequence to have non-disjunction in mitosis? o Example:  Trisomy 21 (Down’s Syndrome) Ploidy level   (2n +1) Offspring will have aneuploidy. Normal offspring –unaffected.
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BICD 100- GENETICS (Ghiara) Spring 08 TA: Michelle Salcedo [email protected] Week 4 What does (2n + 1) mean? Common features of someone who has Trisomy 21:
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This note was uploaded on 01/25/2011 for the course BICD 100 taught by Professor Nehring during the Spring '08 term at UCSD.

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Discussion Section michelle wk 4 -...

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