Lecture_L - Mitochondrion and Electron Transport •...

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Unformatted text preview: Mitochondrion and Electron Transport • Transport systems of the mitochondrion • Structure of the mitochondrion • The electron transport chain • Coenzymes of the electron transport chain • Cytochromes Learning Objectives ADH and FADH 2 The sites of electron transfer that form NADH and FADH 2 in glycolysis and citric acid cycle Fig. 17-1 C 6 H 12 O 6 + 6 H 2 O → 6 CO 2 + 24 H + + 24 e- 6 O 2 + 24 H + + 24 e- → 12 H 2 O Two Half-Reactions of Complete Oxidation of Glucose C 6 H 12 O 6 + 6 O 2 → 6 CO 2 + 6 H 2 O Overall Reaction: Two half-reactions: Glycolysis and citric acid cycle Electron Transport Chain The Fate of Electrons Released upon Glucose Oxidation • The “elementary” steps of the first half-reaction take place in the cytosol (glycolysis) and in the mitochondrion (the citric acid cycle). The released 12 electron pairs reduce 10 NAD + and 2 FAD yielding 10 NADH and 2 FADH 2 . • “Elementary” steps of the second half-reaction take place in the mitochondrion. The 12 electron pairs move from NADH and FADH 2 to the electron transport chain that includes more than 10 redox centers in four enzyme complexes . • The electron transfer pumps protons out of the matrix in the intermembrane space. The resulting electrochemical gradient drives the synthesis of ATP from ADP and P i in the oxidative phosphorylation process. he Mitochondrion...
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Lecture_L - Mitochondrion and Electron Transport •...

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